The Glen Report 36.2

Explore PCR optimization, catalyst-free click reactions, RNA deprotection, new products, and more..

Get the latest Glen Report

Serinol Nucleic Acids

Introducing Serinol Nucleic Acids (SNA): an acyclic phosphodiester backbone derived from serinol, offering enhanced stability and diverse applications in RNA interference, molecular beacons, splice switching, and more.

Explore SNA

2′-OMe-N6-Me-A-CE (^m6A_m) Phosphoramidite

Introducing 2′-OMe-N6-Me-A-CE (^m6A_m) phosphoramidite, vital for developing new cap structures and gene regulation, in support of mRNA cap research.

Discover more about ^m6A_m

5X Tris-Borate-EDTA (TBE) Buffer

Suitable for a wide range of applications including agarose and polyacrylamide gel electrophoresis, plasmid characterization, DNA sequencing gels, and more, offering versatility in nucleic acid analysis.

Get more details

Reagents for Oligonucleotide Synthesis Success

Find the most complete selection of products for DNA and RNA oligonucleotide synthesis

Browse All Products

Gene editing through the blood-brain barrier using ultrasound

Microbubble enhanced focused ultrasound methods are making it possible via systemic administration to deliver drugs to specific deep brain structures. Download the note to learn more.

Download note now

DNA & RNA Nucleosides, Analogs, and Supports

Our reagents for the synthesis of DNA and RNA oligonucleotides are produced and packaged to ensure the highest performance on commercial synthesizers.

Universal Supports and Synthesis Supplies

Our universal supports and synthesis supplies are produced and packaged to ensure the highest performance on commercial oligonucleotide synthesizers.

Ancillary Reagents

Glen Research ancillary reagents are produced and packaged to ensure the highest performance on commercial oligonucleotide synthesizers.

Modification and Labeling

Our products for oligonucleotide modification and labeling are produced and packaged to ensure the highest performance on commercial synthesizers.

Oligonucleotide Purification Supplies

Since the DMT group binds strongly to reverse phase supports, the full-length sequences can be retained in a cartridge while the failure sequences are eluted.

Glen Report Newsletter

Glen Report Volume 36.2 is now available.

Read the Latest Glen Report

Spirocyclopropylene bridged nucleic acid (scpBNA™) Phosphoramidites

Spirocyclopropylene bridged nucleic acid (scpBNATM) is a tricyclic analog of locked nucleic acid (LNA). scpBNA exhibits high binding affinity as well as excellent metabolic stability, and these properties make scpBNA an excellent sugar modification for therapeutic applications. Read more!

Explore Oligonucleotide Applications

Glen Research offers a wide range of products for oligonucleotide applications.

Learn More

Design of Fluorescent Probes

Glen Research offers a wide selection of fluorophores and fluorescence quenchers, which can be added during oligonucleotide synthesis at the 5′- or 3’-terminus or within the sequence. The resultant fluorescent oligonucleotide probes are typically used in a wide variety of applications like genetic and genome analyses, and forensic analysis. Common applications of fluorescent oligonucleotide probes are FRET and Molecular Beacon probes.