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Our reagents for the synthesis of DNA and RNA oligonucleotides are produced and packaged to ensure the highest performance on commercial synthesizers.

Our universal supports and synthesis supplies are produced and packaged to ensure the highest performance on commercial oligonucleotide synthesizers.

Glen Research ancillary reagents are produced and packaged to ensure the highest performance on commercial oligonucleotide synthesizers.

Our products for oligonucleotide modification and labeling are produced and packaged to ensure the highest performance on commercial synthesizers.

Since the DMT group binds strongly to reverse phase supports, the full-length sequences can be retained in a cartridge while the failure sequences are eluted.

 

Glen Report Newsletter

Glen Report Volume 34.2 is now available.

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Featured Article

New Products — LA CPGs

Locked Nucleic Acid (LNA) is a modified ribonucleic acid containing a methylene bridge connecting the 2’-oxygen and 4’-carbon atoms. Oligonucleotides modified with (LNA), are prominent for hybridization assays and probes due to enhanced thermal stability towards complementary oligos, without compromising base pairing specificity. Each LNA modification can increase the melting temperature of a duplex by 2-8 °C. LNAs are commonly employed in antisense oligonucleotides ASOs as gapmers or mixers.

Explore Oligonucleotide Applications

Glen Research offers a wide range of products for oligonucleotide applications.

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Design of Fluorescent Probes

Glen Research offers a wide selection of fluorophores and fluorescence quenchers, which can be added during oligonucleotide synthesis at the 5′- or 3’-terminus or within the sequence. The resultant fluorescent oligonucleotide probes are typically used in a wide variety of applications like genetic and genome analyses, and forensic analysis. Common applications of fluorescent oligonucleotide probes are FRET and Molecular Beacon probes.

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