Aptamer Development

Aptamers, generated through repetitive selection using SELEX or an equivalent in vivo procedure, are chosen for their ability to bind desired target molecules, which are frequently small molecules useful in therapeutics. In some ways, they may be described as chemically engineered versions of antibodies. Of course, nucleic acid aptamers have advantages over antibodies in that they can be developed rapidly by in vitro methods, taking advantage of the reproducibility of chemical oligonucleotide synthesis and the inherent stability of modified oligonucleotides. A full battery of base, sugar and inter-nucleotide modifications is available for aptamer development.

4 Product Results
 
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  • beta-L-iPr-Pac-dG-CE Phosphoramidite
    beta-L-iPr-Pac-dG-CE Phosphoramidite (10-2121)
    Catalog #: 10-2121
    Formal Name:

    5'-Dimethoxytrityl-N-p-isopropyl-phenoxyacetyl-beta-L-2'-deoxyGuanosine,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite

  • beta-L-Pac-dA-CE Phosphoramidite
    beta-L-Pac-dA-CE Phosphoramidite (10-2101)
    Catalog #: 10-2101
    Formal Name:

    5'-Dimethoxytrityl-N-phenoxyacetyl-beta-L-2'-deoxyAdenosine,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite

  • beta-L-Ac-dC-CE Phosphoramidite
    beta-L-Ac-dC-CE Phosphoramidite (10-2115)
    Catalog #: 10-2115
    Formal Name:

    5'-Dimethoxytrityl-N-acetyl-beta-L-2'-deoxyCytidine,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite

  • beta-L-dT-CE Phosphoramidite
    beta-L-dT-CE Phosphoramidite (10-2130)
    Catalog #: 10-2130  |  CAS #: 141846-55-1
    Formal Name:

    5'-Dimethoxytrityl-beta-L-2'-deoxyThymidine,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite

 
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