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Glen UnySupport for Oligonucleotide Synthesis

The challenge for first generation universal supports was that complete dephosphorylation using ammonium hydroxide, AMA or anhydrous methylamine gas takes longer than most companies wish to allocate. A more recent development has been the use of a support based on a molecule which is "conformationally preorganized" to accelerate the dephosphorylation reaction. By using a rigid bicyclic molecule on the support, the rate of elimination is markedly faster than earlier universal supports. We are happy to offer Glen UnySupport in a variety of popular formats under license from Ionis Pharmaceuticals


INTELLECTUAL PROPERTY

This product is covered by US Patent 7,202,264 owned by Ionis Pharmaceuticals, Inc.. 

6 Product Results
 
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  • Glen UnySupport™ PS
    Glen UnySupport™ PS (26-5040)
    Catalog #: 26-5040
    Formal Name: N-Methyl-succinimido[3,4-b]-7-oxabicyclo[2.2.1]heptane-6-(4,4'-dimethoxytrityloxy)-5-succinoyl-polystyrene
  • High Load Glen UnySupport™
    High Load Glen UnySupport™ (25-5040)
    Catalog #: 25-5040
    Formal Name: N-Methyl-succinimido[3,4-b]-7-oxabicyclo[2.2.1]heptane-6-(4,4'-dimethoxytrityloxy)-5-succinoyl long chain alkylamino CPG
  • Glen UnySupport™ FC
    Glen UnySupport™ FC (22-5041)
    Catalog #: 22-5041
    Formal Name:

    N-Methyl-succinimido[3,4-b]-7-oxabicyclo[2.2.1]heptane-6-(4,4'-dimethoxytrityloxy)-5-diglycoloyl-long chain alkylamino CPG
  • Glen UnySupport™ 1000
    Glen UnySupport™ 1000 (20-5041)
    Catalog #: 20-5041
    Formal Name: N-Methyl-succinimido[3,4-b]-7-oxabicyclo[2.2.1]heptane-6-(4,4'-dimethoxytrityloxy)-5-succinoyl long chain alkylamino CPG
  • Glen UnySupport™ 500
    Glen UnySupport™ 500 (20-5040)
    Catalog #: 20-5040
    Formal Name: N-Methyl-succinimido[3,4-b]-7-oxabicyclo[2.2.1]heptane-6-(4,4'-dimethoxytrityloxy)-5-succinoyl long chain alkylamino CPG
  • Female-Female Luer Adapter
    Female-Female Luer Adapter (20-0060)
    Catalog #: 20-0060
    Formal Name:

    We offer the female-female luers required for use of the Glen UnySupport Frits on Expedite and ABI 394 instruments. To assemble the column, simply place the frit in the luer fitting and seat it in the center using an allen wrench or equivalent tool (be careful not to puncture the frit). The luers are re-useable and can be purchased in packs of 10
 
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