Glen UnySupport for Oligonucleotide Synthesis

The challenge for first generation universal supports was that complete dephosphorylation using ammonium hydroxide, AMA or anhydrous methylamine gas takes longer than most companies wish to allocate. A more recent development has been the use of a support based on a molecule which is "conformationally preorganized" to accelerate the dephosphorylation reaction. By using a rigid bicyclic molecule on the support, the rate of elimination is markedly faster than earlier universal supports. We are happy to offer Glen UnySupport in a variety of popular formats under license from Ionis Pharmaceuticals


INTELLECTUAL PROPERTY

This product is covered by US Patent 7,202,264 owned by Ionis Pharmaceuticals, Inc.. 

6 Product Results
 
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  • Glen UnySupport™ PS
    Glen UnySupport™ PS (26-5040)
    Catalog #: 26-5040
    Formal Name: N-Methyl-succinimido[3,4-b]-7-oxabicyclo[2.2.1]heptane-6-(4,4'-dimethoxytrityloxy)-5-succinoyl-polystyrene
  • High Load Glen UnySupport™
    High Load Glen UnySupport™ (25-5040)
    Catalog #: 25-5040
    Formal Name: N-Methyl-succinimido[3,4-b]-7-oxabicyclo[2.2.1]heptane-6-(4,4'-dimethoxytrityloxy)-5-succinoyl long chain alkylamino CPG
  • Glen UnySupport™ 1400
    Glen UnySupport™ 1400 (20-5044)
    Catalog #: 20-5044
    Formal Name: N-Methyl-succinimido[3,4-b]-7-oxabicyclo[2.2.1]heptane-6-(4,4'-dimethoxytrityloxy)-5-succinoyl long chain alkylamino CPG
  • Glen UnySupport™ 2000
    Glen UnySupport™ 2000 (20-5042)
    Catalog #: 20-5042
    Formal Name: N-Methyl-succinimido[3,4-b]-7-oxabicyclo[2.2.1]heptane-6-(4,4'-dimethoxytrityloxy)-5-succinoyl long chain alkylamino CPG
  • Glen UnySupport™ 1000
    Glen UnySupport™ 1000 (20-5041)
    Catalog #: 20-5041
    Formal Name: N-Methyl-succinimido[3,4-b]-7-oxabicyclo[2.2.1]heptane-6-(4,4'-dimethoxytrityloxy)-5-succinoyl long chain alkylamino CPG
  • Glen UnySupport™ 500
    Glen UnySupport™ 500 (20-5040)
    Catalog #: 20-5040
    Formal Name: N-Methyl-succinimido[3,4-b]-7-oxabicyclo[2.2.1]heptane-6-(4,4'-dimethoxytrityloxy)-5-succinoyl long chain alkylamino CPG
 
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