Home Products DNA & RNA Nucleosides, Analogs, and Supports Natural RNA Phosphoramidites and Supports 2'-O-Me Phosphoramidites and Supports for RNA Synthesis 2'-OMe Phosphoramidites for RNA Synthesis 2'-OMe-Ac-C-CE Phosphoramidite

2'-OMe-Ac-C-CE Phosphoramidite - (10-3115)

5'-Dimethoxytrityl-N-acetyl-Cytidine,2'-O-methyl,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite

As low as $15.00

In stock

Only %1 left

default

10-3115

Product	Options
	To retrieve a catalog number, please select a pack size and format: Copy link to this configuration Size Format See Compatibility Chart 4. Select Your Quantity: Request a quote 3. Price

Product Specifications

Formula:

C₄₂H₅₂N₅O₉P

M.W.:

801.88

F.W.:

319.21

CAS Number:

199593-09-4

5'-Dimethoxytrityl-N-acetyl-Cytidine,2'-O-methyl,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite

Description

Glen Research 2'-OMe-RNA CE (ß-cyanoethyl) Phosphoramidites are designed to produce synthetic oligonucleotides containing nuclease resistant 2'-O-methyl ribonucleotide linkages. Deprotection, isolation and handling of 2'-O-methyl oligonucleotides are identical to the procedures for oligodeoxynucleotides.

Details

Usage

Coupling: 6 minute coupling time
Deprotection: No changes needed from standard method recommended by synthesizer manufacturer.

Specifications
Diluent	Anhydrous Acetonitrile
Recommended Storage	Refrigerated storage, maximum of 2-8°C, dry
Stability In Solution	3-5 days

Dilution/Coupling Data

The table below show pack size data and, for solutions, dilution and approximate coupling based on normal priming procedures.

ABI 392/394

Catalog #	Pack Size	Grams/Pack	0.1M Dil. (mL)	Approximate Number of Additions
				LV40	LV200	40nm	0.2μm	1μm	10μm
10-3115-02	0.25 g	.25grams	3.12	90.67	54.4	34	24.73	18.13	4.53
10-3115-05	0.5 g	.5grams	6.24	194.67	116.8	73	53.09	38.93	9.73
10-3115-10	1.0 g	1grams	12.47	402.33	241.4	150.88	109.73	80.47	20.12
10-3115-90	100 µmol	.08grams	1	20	12	7.5	5.45	4	1

Expedite

Catalog #	Pack Size	Grams/Pack	Dilution (mL)	Approximate Number of Additions
				Molarity	50nm	0.2μm	1μm	15μm
10-3115-02	0.25 g	.25grams	4.65	0.07	86.6	54.13	39.36	5.41
10-3115-05	0.5 g	.5grams	9.31	0.07	179.8	112.38	81.73	11.24
10-3115-10	1.0 g	1grams	18.61	0.07	365.8	228.63	166.27	22.86
10-3115-90	100 µmol	.08grams	1.5	0.07	23.6	14.75	10.73	1.48