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Amino-Modifier C6 dR - (10-1911)

5'-O-Dimethoxytrityl-1'-O-[(6-trifluoroacetylamino)-hexyl]-2'-deoxyribose-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
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10-1911
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Product Specifications

Formula:
C43H57F3N3O8P
M.W.:
831.91
F.W.:
295.27
CAS Number:
N/A
5'-O-Dimethoxytrityl-1'-O-[(6-trifluoroacetylamino)-hexyl]-2'-deoxyribose-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Description
The Amino-Modifier C6 dR is an internal amino modifier that can be incorporated multiple times in an oligonucleotide. This beta anomer is susceptible to nuclease cleavage, which offers an additional conjugation strategy, one that can be useful in probe design by taking advantage of its nuclease sensitivity.
Details

Usage

  • Coupling: No changes needed from standard method recommended by synthesizer manufacturer.
  • Deprotection: No changes needed from standard method recommended by synthesizer manufacturer.
Specifications
Diluent Anhydrous Acetonitrile
Recommended Storage Freezer storage; -10 to -30°C, dry
Stability In Solution 1-2 Days
Certificate of analysis

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