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5'-OMe-dT-CE Phosphoramidite - (10-1031)

5'-O-methyl-2'-deoxyThymidine,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite

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10-1031

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Product Specifications

Formula:

C₂₀H₃₃N₄O₆P

M.W.:

456.48

F.W.:

318.22

CAS Number:

149681-62-9

5'-O-methyl-2'-deoxyThymidine,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite

Description

In situations where ligation must be blocked at the 5' terminus, 5'-OMe-dT may be used. 5'-OMe modification of a strand of siRNA using 5'-OMe-T can control guide strand selection and targeting specificity.1

Details

Usage

Coupling: No changes needed from standard method recommended by synthesizer manufacturer.
Deprotection: No changes needed from standard method recommended by synthesizer manufacturer.|(Note: this product is a 5'-terminator.)