Sulfurizing Reagent II

Product Specifications

Formula:

C₅H₇N₃S₃

M.W.:

205.31

CAS Number:

1192027-04-5

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Technical Documents

Safety Data Sheet

Sulfurizing Reagent !! - Stable in Solution and Optimized for RNA Sulfurizaion

Safety Data Sheet

Glen Report 18.13: Sulfurizing Reagent II - Stable in Solution and Optimized for RNA Sulfurization

Glen Report 6.23: Research Review - Antisense RNA

Glen Report 18-1 Supplement: Sulfurizing Reagent II and its use in Synthesizing Oligonucleotide Phosphorothioates

Glen Report 4-16: Sulfurization of Oligonucleotides

Glen Report 32-27: Technical Snippets

Sulfurizing Reagent II

Coupling: Sulfurizing: A 60 second sulfurization step time for DNA or a 360 second sulfurization step time for RNA is recommended. Sulfurization step must come before capping step to minimize phosphodiester formation.
Deprotection: See TB_Sulfurizing II.pdf

Specifications
Diluent	60% pyridine/40% Acetonitrile (fully dissolve in pyridine first, see notes below*)
Storage	Controlled room temperature or lower, dry
Stability	At least 6 months