Glen Report 27.15: PC Modifiers
Glen Research introduced PC Biotin and related PC modifiers in 2001. We are delighted to be able to publish this article illustrating the use of PC Biotin (1) in aptamer development at SomaLogic, Inc. We especially thank Jeff Carter for providing us with this article.
Our range of PC phosphoramidites is shown in Figure 3. PC Amino-Modifier (2) is useful for conjugating an NHS ester labelled tag post oligo synthesis, while PC Spacer (3) allows tags to be added to oligonucleotides as phosphoramidites.



Glen Research offers PC Biotin, PC Amino-Modifier and PC Spacer products in association with AmberGen, Inc. and Link Technologies, Ltd. For a commercial application license, please contact AmberGen, Inc., +617-975-0680, http://www.ambergen.com/.
Also see: Photocleavable biotin linker for use in SOMAscanâ„¢
Product Information
PC Biotin Phosphoramidite (10-4950)
PC Amino-Modifier Phosphoramidite (10-4906)
PC Spacer Phosphoramidite (10-4913)
- Glen Report 27.11: Reversible Photo-Switching of DNA Function with Azobenzene-Tethered DNA
- Glen Report 27.12: New Products - Dithiol Serinol Phosphoramidite and 3’- Dithiol Serinol CPG
- Glen Report 27.13: Technical Brief - APA: An Alternative to AMA Deprotection
- Glen Report 27.14: Photocleavable Biotin Linker for Use in SOMAscanâ„¢
- Glen Report 27.15: PC Modifiers
- Glen Report 27.16: Technical Brief - Capping and Trityl-Protected Amino-Modifiers
- Glen Report 27.17: Technical Brief - DBCO-dT - An Unusual Case of Iodine Sensitivity