DNP Labeling of Oligonucleotides
An analytical test based on detection of 2,4-dinitrophenyl (DNP) labeled oligonucleotides with anti-DNP antibodies has been proposed. We have chosen the branched triethylene glycol (TEG) spacer in our version of DNP phosphoramidite since it can be added once or several times to the 3’ or 5’ terminus.
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