Methacrylate C6 Phosphoramidite - (10-1891)

Methacrylate C6 Phosphoramidite is a terminus modifier that attaches a methacrylate functional group to an oligonucleotide.  Methacrylate-modified oligonucleotides can be reacted with thiol-modified surfaces or incorporated into polyacrylamide gels. Methacrylate-modified oligonucleotides have been used to generate oligonucleotide labeled hydrogels, microspheres, microarrays, and functionalized polymeric surfaces, among other applications. These oligonucleotide-labeled surfaces and polymers have been used for purification, hybridization detection, PCR amplification, affinity capture, aptamers, sequencing, and biosensors.  Recent applications of methacrylate-labeled oligonucleotides include aptamer-based hydrogels, molecular imprinting, and Expansion Microscopy.