3'-Glyceryl CPG - (20-2902)
3-[(4,4'-Dimethoxytrityoxy)glyceryl-1-succinoyl]-long chain alkylamino-CPG
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20-2902
3-[(4,4'-Dimethoxytrityoxy)glyceryl-1-succinoyl]-long chain alkylamino-CPG
Description
With Glyceryl CPG, the 3’-terminus of an oligonucleotide is readily oxidized by sodium periodate to form a 3’-phosphoglycaldehyde. The aldehyde may be further oxidized to the corresponding carboxylic acid. Either the aldehyde or the carboxylate may be used for subsequent conjugation to amine-containing products.
Details
Usage
- Coupling: This support should be used in a manner identical to normal protected nucleoside support since it contains the DMT group.
- Deprotection: Cleavage of the oligonucleotide from this support requires 2 hours at room temperature with ammonium hydroxide. Complete the deprotection using the protocol required by the nucleobases.
| Specifications | |
|---|---|
| Recommended Storage | Freezer storage, -10 to -30°C, dry |
Technical documents
Certificate of analysis
CoA search tool
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