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iPr-Pac-G-RNA-CPG - (20-3321)

5'-Dimethoxytrityl-N-isopropyl-phenoxyacetyl-Guanosine,2'-acetate-3'-succinoyl-long chain alkylamino-CPG

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20-3321

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Product Specifications

F.W.:

345.21

Pore Size:

1000Å

5'-Dimethoxytrityl-N-isopropyl-phenoxyacetyl-Guanosine,2'-acetate-3'-succinoyl-long chain alkylamino-CPG

Description

Glen Research offers RNA supports in which protected ribonucleosides are attached to CPG. With 5'-DMT protection, and all other protecting groups base-labile, the use of these supports is identical to DNA supports. These supports are suitable for use in producing oligodeoxynucleotides modified at the 3'-terminus or oligoribonucleotides.

Details

Usage

Coupling: Please refer to the technical bulletin for the synthesis and deprotection procedures. This support should be used in a manner identical to normal protected nucleoside support since it contains the DMT group. To avoid any exchange of the iPr-Pac group on the dG with acetyl, use the UltraMild Cap Mix A (40-4210-xx/ 40-4212-xx).
Deprotection: Deprotect using the protocol required by the nucleobases.