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Glen UnySupport for Oligonucleotide Synthesis

The challenge for first generation universal supports was that complete dephosphorylation using ammonium hydroxide, AMA or anhydrous methylamine gas takes longer than most companies wish to allocate. A more recent development has been the use of a support based on a molecule which is "conformationally preorganized" to accelerate the dephosphorylation reaction. By using a rigid bicyclic molecule on the support, the rate of elimination is markedly faster than earlier universal supports. We are happy to offer Glen UnySupport in a variety of popular formats under license from Ionis Pharmaceuticals

Intellectual Property

This product is covered by US Patent 7,202,264 owned by Ionis Pharmaceuticals, Inc.

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