Glen Research offers RNA supports in which protected ribonucleosides are attached to CPG. With 5'-DMT protection, and all other protecting groups base-labile, the use of these supports is identical to DNA supports. These supports are suitable for use in producing oligodeoxynucleotides modified at the 3'-terminus or oligoribonucleotides.
Coupling: Please refer to the technical bulletin for the synthesis and deprotection procedures. This support should be used in a manner identical to normal protected nucleoside support since it contains the DMT group.
Deprotection: Deprotect using the protocol required by the nucleobases.