Glen-Pak™ DNA purification cartridge

To Retrieve a Catalog Number, Select a Pack Size and Format:


Glen-Pak™ DNA and RNA cartridges have advantages over Poly-Pak cartridges in that a single loading of the diluted crude deprotection solution is all that is necessary. Also, the range of purification has been extended to 100+ using DMT-on oligos. Glen-Pak cartridges have similar performance to Fluoro-Pak cartridges but without the need for the fluorous DMT group at the 5' terminus and special phosphoramidites, so the cost is lower. In addition, Glen-Pak cartridges allow purification of virtually the complete range of dyes and modifiers. The Glen-Pak DNA Cartridge 3g is a large cartridge capable of purifying 10-20 µmole oligonucleotide syntheses using the standard DMT-on procedure and Glen-Pak DNA 30mg 96-Well Plates are for parallel purification of up to 50 nmole scale syntheses. The Glen-Pak DNA 3mg 384-Well Plate is designed for use with 384-well plate compatible vacuum manifold systems and can purify up to a 20 nmole scale synthesis. Each well contains 3mg of Glen-Pak DNA resin, which binds about 15 nmoles of full length 40-mer DMT-ON oligo. 

Scale suggestions for the Glen-Pak DNA product line are shown below:

Glen-Pak DNA Product Catalog Number Synthesis Scale Compatibility
Glen-Pak DNA 50mg Purification Cartridge 60-5000-96 0 nmole - 200 nmole
Glen-Pak DNA Purification Cartridge 60-5100-XX and 60-5200-XX 10 nmole - 1.0 µmole
Glen-Pak DNA Cartridge 3G 60-5300-01 5 µmole - 20 µmole
Glen-Pak DNA 30 mg 96-Well Plate 60-5400-01 10 nmole - 50 nmole
Glen-Pak DNA 3mg 384-Well Plate 60-5500-xx up to 20 nmoles

A User Guide to Glen-Pak™ Purification describes in detail the process and several applications for DNA and RNA purification.
This booklet is available online at:


Storage Controlled room temperature


An artificial triazole backbone linkage provides a split-and-click strategy to bioactive chemically modified CRISPR sgRNA Lapatrada Taemaitree, Arun Shivalingam, Afaf H. El-Sagheer & Tom Brown

NAD+-dependent RNA terminal 2' and 3' phosphomonoesterase activity of a sub-set of Tpt1 enzymes Munir A, Abdullahu L, Banerjee A, Damha MJ, Shuman S

Technical capabilities and limitations of optical spectroscopy and calorimetry using water-miscible solvents: The case of dimethyl sulfoxide, acetonitrile and 1,4-dioxane Hirano, A. et al.

RIG-I Recognition of RNA Targets: The Influence of Terminal Base Pair Sequence and Overhangs on Affinity and Signaling Ren, X., Linehan, M. M., Iwasaki, A., & Pyle, A. M.

2-Aminopyridine as a Nucleobase Substitute for Adenine in DNA-Like Architectures: Synthesis of Alkynyl C-Nucleotides and their Hybridization Characteristics Kurosaki, F., Chiba, J., Oda, Y., Hino, A., & Inouye, M.

The effector mechanism of siRNA spherical nucleic acids Yamankurt, G., Stawicki, R. J., Posadas, D. M., Nguyen, J. Q., Carthew, R. W., & Mirkin, C. A.

Anomalous reverse transcription through chemical modifications in polyadenosine stretches Kladwang, W., Topkar, V. V., Liu, B., Hodges, T. L., Keane, S. C., al-Hashimi, H., & Das, R.

Data on multimerization efficiency for short linear DNA templates and phosphoryl guanidine primers during isothermal amplification with Bst exo- DNA polymerase Garafutdinov, R. R., Sakhabutdinova, A. R., Kupryushkin, M. S., & Pyshnyi, D. V.

Structural polymorphism driven by a register shift in a CGAG-rich region found in the promoter of the neurodevelopmental regulator AUTS2 gene Ales Novotny, Janez, and Vojc Kocman