Glen-Pak™ DNA purification cartridge

To Retrieve a Catalog Number, Select a Pack Size and Format:


Glen-Pak™ DNA and RNA cartridges have advantages over Poly-Pak cartridges in that a single loading of the diluted crude deprotection solution is all that is necessary. Also, the range of purification has been extended to 100+ using DMT-on oligos. Glen-Pak cartridges have similar performance to Fluoro-Pak cartridges but without the need for the fluorous DMT group at the 5' terminus and special phosphoramidites, so the cost is lower. In addition, Glen-Pak cartridges allow purification of virtually the complete range of dyes and modifiers. The Glen-Pak DNA Cartridge 3g is a large cartridge capable of purifying 10-20 µmole oligonucleotide syntheses using the standard DMT-on procedure and Glen-Pak DNA 30mg 96-Well Plates are for parallel purification of up to 50 nmole scale syntheses. The Glen-Pak DNA 3mg 384-Well Plate is designed for use with 384-well plate compatible vacuum manifold systems and can purify up to a 20 nmole scale synthesis. Each well contains 3mg of Glen-Pak DNA resin, which binds about 15 nmoles of full length 40-mer DMT-ON oligo. 

Scale suggestions for the Glen-Pak DNA product line are shown below:

Glen-Pak DNA Product Catalog Number Synthesis Scale Compatibility
Glen-Pak DNA 50mg Purification Cartridge 60-5000-96 0 nmole - 200 nmole
Glen-Pak DNA Purification Cartridge 60-5100-XX and 60-5200-XX 10 nmole - 1.0 µmole
Glen-Pak DNA Cartridge 3G 60-5300-01 5 µmole - 20 µmole
Glen-Pak DNA 30 mg 96-Well Plate 60-5400-01 10 nmole - 50 nmole
Glen-Pak DNA 3mg 384-Well Plate 60-5500-xx up to 20 nmoles

A User Guide to Glen-Pak™ Purification describes in detail the process and several applications for DNA and RNA purification.
This booklet is available online at:


Storage Controlled room temperature


An artificial triazole backbone linkage provides a split-and-click strategy to bioactive chemically modified CRISPR sgRNA Lapatrada Taemaitree, Arun Shivalingam, Afaf H. El-Sagheer & Tom Brown

NAD+-dependent RNA terminal 2' and 3' phosphomonoesterase activity of a sub-set of Tpt1 enzymes Munir A, Abdullahu L, Banerjee A, Damha MJ, Shuman S

Technical capabilities and limitations of optical spectroscopy and calorimetry using water-miscible solvents: The case of dimethyl sulfoxide, acetonitrile and 1,4-dioxane Hirano, A. et al.

RIG-I Recognition of RNA Targets: The Influence of Terminal Base Pair Sequence and Overhangs on Affinity and Signaling Ren, X., Linehan, M. M., Iwasaki, A., & Pyle, A. M.

2-Aminopyridine as a Nucleobase Substitute for Adenine in DNA-Like Architectures: Synthesis of Alkynyl C-Nucleotides and their Hybridization Characteristics Kurosaki, F., Chiba, J., Oda, Y., Hino, A., & Inouye, M.

The effector mechanism of siRNA spherical nucleic acids Yamankurt, G., Stawicki, R. J., Posadas, D. M., Nguyen, J. Q., Carthew, R. W., & Mirkin, C. A.

Anomalous reverse transcription through chemical modifications in polyadenosine stretches Kladwang, W., Topkar, V. V., Liu, B., Hodges, T. L., Keane, S. C., al-Hashimi, H., & Das, R.

Data on multimerization efficiency for short linear DNA templates and phosphoryl guanidine primers during isothermal amplification with Bst exo- DNA polymerase Garafutdinov, R. R., Sakhabutdinova, A. R., Kupryushkin, M. S., & Pyshnyi, D. V.

Structural polymorphism driven by a register shift in a CGAG-rich region found in the promoter of the neurodevelopmental regulator AUTS2 gene Ales Novotny, Janez, and Vojc Kocman

A sodium/potassium switch for G4-prone G/C-rich sequences Yu Luo, Martina Lenarcic Zivkovic, Jiwawei Wang, Jan Rynes, Silvie Foldynova-Trantirkova, Lukas Trantirek, Daniela Verga, and Jean-Louis Mergny.

An Acid-Free Deprotection of 5_-Amino-Modified Oligonucleotides Richard L. Redman, Yonghao Jin, Juan R. Aguilera, Dillon T. Flood & Kyle W. Knouse

Defined covalent attachment of three cancer drugs to DNA origami increases cytotoxicity at nanomolar concentration Natalia Navarro, Anna Aviñó, Òscar Domènech, Jordi Borrell, Ramon Eritja, and Carme Fàbrega

Transient states during the annealing of mismatched and bulged oligonucleotides Marco Todisco, Dian Ding, and Jack W. Szostak