1. Home
  2. Products
  3. DNA & RNA Nucleosides, Analogs, and Supports
  4. Nucleoside Analog Phosphoramidites
  5. DNA Nucleoside Analogs
  6. Analog Phosphoramidites for Structural Studies
  7. Halogenated Nucleosides
Products

Halogenated Nucleosides

Brominated and iodinated nucleosides are used in X-ray crystallography studies of oligonucleotide structure.  They are also photolabile and are used for cross-linking studies to probe the structure of protein-DNA complexes.  Antibodies exist to Br-dU and oligonucleotides containing Br-dU can be used as probes.  5-Fluoro-dU can be used as a non-photoreactive alternative to 5-Br-dU with similar electron density.  5-F-dU base pairs more strongly that T to both dA and the dG mismatch.  It is also useful for probing DNA structure using 19F NMR spectroscopy.

6 Product Results
 
per page
  • 8-Br-dA-CE Phosphoramidite
    8-Br-dA-CE Phosphoramidite (10-1007)
    Catalog #: 10-1007  |  CAS #: 207906-54-5
    Formal Name: 5'-Dimethoxytrityl-N6-dimethylaminomethylidene-8-bromo-2'-deoxyAdenosine,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
  • 8-Br-dG-CE Phosphoramidite
    8-Br-dG-CE Phosphoramidite (10-1027)
    Catalog #: 10-1027  |  CAS #: 198080-37-4
    Formal Name: 5'-Dimethoxytrityl-N2-dimethylaminomethylidene-8-bromo-2'-deoxyGuanosine,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
  • 5-Br-dC-CE Phosphoramidite
    5-Br-dC-CE Phosphoramidite (10-1080)
    Catalog #: 10-1080  |  CAS #: 178925-43-4
    Formal Name: 5'-Dimethoxytrityl-N-benzoyl-5-bromo-2'-deoxyCytidine,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
  • 5-I-dC-CE Phosphoramidite
    5-I-dC-CE Phosphoramidite (10-1081)
    Catalog #: 10-1081  |  CAS #: 178925-44-5
    Formal Name: 5'-Dimethoxytrityl-N-benzoyl-5-iodo-2'-deoxyCytidine,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
  • 5-Br-dU-CE Phosphoramidite
    5-Br-dU-CE Phosphoramidite (10-1090)
    Catalog #: 10-1090  |  CAS #: 142246-64-8
    Formal Name: 5'-Dimethoxytrityl-5-bromo-2'-deoxyUridine,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
  • 5-I-dU-CE Phosphoramidite
    5-I-dU-CE Phosphoramidite (10-1091)
    Catalog #: 10-1091  |  CAS #: 178925-48-9
    Formal Name: 5'-Dimethoxytrityl-5-iodo-2'-deoxyUridine,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
 
per page