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5'-Bromohexyl Phosphoramidite
6-Bromo-hex-1-yl-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite
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Description
Specific to the 5’-terminus, 5’-Bromohexyl Phosphoramidite is added in the last cycle. This modifier can then be easily transformed into a 5’-azido group by displacement of bromide using sodium azide.2
Details
Specifications
Diluent Anhydrous Acetonitrile
Storage Freezer storage, -10 to -30°C, dry
Stability 1-2 days
Dilution/Coupling Data
The table below show pack size data and, for solutions, dilution and approximate coupling based on normal priming procedures.
ABI 392/394
Catalog #
Pack Size
Grams/Pack
0.1M Dil. (mL)
Approximate Number of Additions
LV40
LV200
40nm
0.2μm
1μm
10μm
10-1946-02
0.25 g
.25grams
6.56
205.33
123.2
77
56
41.07
10.27
10-1946-90
100 µmol
.038grams
1
20
12
7.5
5.45
4
1
Expedite
Catalog #
Pack Size
Grams/Pack
Dilution (mL)
Approximate Number of Additions
Molarity
50nm
0.2μm
1μm
15μm
10-1946-02
0.25 g
.25grams
9.79
0.07
189.4
118.38
86.09
11.84
10-1946-90
100 µmol
.038grams
1.5
0.07
23.6
14.75
10.73
1.48
References
REFERENCES|(2) J. Lietard, A. Meyer, J.J. Vasseur, and F. Morvan, Tetrahedron Letters, 2007, 48, 8795-8798.
