Sulfurizing Reagents

Glen Research's Sulfurizing Reagents are used to prepare phosphorothioate linkages using CE phosphoramidite chemistry. Each reagent exhibits the following attributes:

1 Reliably soluble, making them safe to use on automated synthesizers.

2 Reaction is fast (30 seconds), making the process convenient on small scales and readily amenable to scale-up.

3 Process is efficient, with better than 96% of the linkages being phosphorothioate and the remainder being phosphodiester.