Structural Studies Research Products

Glen Research offers a wide range of products for research in structural studies.


Explore Analog Phosphoramidites for Structural Studies

A wide variety of modified DNA bases are available that may be used to investigate the effect on the activity of an oligonucleotide when key structural elements are changed.

Brominated and iodinated nucleosides are used in X-ray crystallography studies of oligonucleotide structure.  They are also photolabile and are used for cross-linking studies to probe the structure of protein-DNA complexes.  Antibodies exist to Br-dU and oligonucleotides containing Br-dU can be used as probes. 

A unique feature of 2'-5' linked oligonucleotides is their ability to bind selectively to complementary RNA.