In situations where ligation must be blocked at the 5' terminus, 5'-OMe-dT may be used. 5'-OMe modification of a strand of siRNA using 5'-OMe-T can control guide strand selection and targeting specificity.1
Details
Usage
Coupling: No changes needed from standard method recommended by synthesizer manufacturer.
Deprotection: No changes needed from standard method recommended by synthesizer manufacturer.|(Note: this product is a 5'-terminator.)
Specifications
Diluent
Anhydrous Acetonitrile
Storage
Freezer storage, -10 to -30°C, dry
Stability
24 hours
Dilution/Coupling Data
The table below show pack size data and, for solutions, dilution and approximate coupling based on normal priming procedures.