Glen Research Product Information

Catalog Number: 20-3315-xx
Description: Ac-C-RNA-CPG

5'-Dimethoxytrityl-N-acetyl-Cytidine,2'-acetate-3'-succinoyl- long chain alkylamino-CPG

 
 
F.W.: 305.18 

Coupling: Please refer to the technical bulletin for the synthesis and deprotection procedures. This support should be used in a manner identical to normal protected nucleoside support since it contains the DMT group.

Deprotection: Deprotect using the protocol required by the nucleobases.

Storage: Controlled room temperature or lower, dry

Stability in Solution: Not Applicable

   

Pricing Information

Catalog Number

Pack Size

Price (US$)


20-3315-01
0.1g
40.00
20-3315-02
0.25g
95.00
20-3315-10
1.0g
355.00
20-3415-41
Pack of 4
100.00
20-3415-42
Pack of 4
75.00
20-3415-13
Pack of 1
225.00
20-3415-14
Pack of 1
300.00

Related Document(s)


Literature Highlight(s)

FREQUENTLY ASKED TECHNICAL QUESTION

QUESTION: Are any changes required from standard DNA synthesis and deprotection?

RESPONSE:These supports (20-3303, 20-3315, 20-3324, 20-3330) can be used for oligodeoxynucleotide synthesis when a ribose functionality is desired at the 3'-terminus. Following periodate oxidation of the 1,2-diol, labelling or carrier molecules containing amino groups can be conjugated to the 3'-terminus. An example (1) is the use of poly-lysine as a carrier molecule.

These supports can be used for RNA synthesis, and our other RNA supports (now all containing 2'-acetyl protecting groups, which are completely base-labile) can also be used for DNA modification.

REFERENCE(S):
(1a) M. Lemaitre, B. Bayard, and B. Lebleu, Proc. Natl. Acad. Sci. USA, 1987, 84, 648-652.
(1b) M. Lemaitre, C. Bisbal, B. Bayard, and B. Lebleu, Nucleosides & Nucleotides, 1987, 6, 311-315.


 

 

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02/20/2019

 

 

 

 

 

 

 

 

 

 

 

 

 

 


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