Glen Research Product Information

Catalog Number: 10-1098-xx
Description: 8,5'-Cyclo-dA CE Phosphoramidite

5'-Dimethoxytrityl-N-benzoyl-(5’S)-8,5'-cyclo-2'-deoxyAdenosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite

Formula: C47H50N7O7
M.W.: 855.92 
F.W.: 311.19 

Diluent: Anhydrous Acetonitrile/Dichloromethane 1:3 (v/v)

Coupling: 3 minute coupling time is recommended. Due to the steric hindrance at the 5' hydroxyl, the coupling time for the phosphoramidite immediately following the addition of the 8,5'-Cyclo-dA should be increased to 6 minutes.

Deprotection: No changes needed from standard method recommended by synthesizer manufacturer.

Storage: Freezer storage, -10 to -30°C, dry

Stability in Solution: 2-3 days

   

Pricing Information

Catalog Number

Pack Size

Price (US$)


10-1098-95
50µm
950.00
10-1098-90
100µm
1850.00
10-1098-02
0.25g
5350.00

Related Document(s)

  

Literature Highlight(s)

DILUTION/COUPLING DATA

The table below shows pack size data and, for solutions, dilutions and approximate couplings based on normal priming procedures. Please link for more detailed usage information with the various synthesizers.

ABI 392/394
Cat.No.Pack
Size
Grams/
Pack
0.1M Dil.
(mL)
LV40LV20040nm0.2µm1µm10µm
Approximate Number of Additions
10-1098-9550µmoles.043grams.53.3321.25.91.67.17
10-1098-90100µmoles.086grams120127.55.4541
10-1098-020.25grams.25grams2.928450.431.522.9116.84.2
Expedite
Cat.No.Pack
Size
Grams/
Pack
Dilution
(mL)
Molarity50nm0.2µm1µm15µm
Approximate Number of Additions
10-1098-9550µmoles.043grams.75.078.65.383.91.54
10-1098-90100µmoles.086grams1.5.0723.614.7510.731.48
10-1098-020.25grams.25grams4.36.0780.850.536.735.05

 

 

VIEW PRINTABLE VERSION

 

 


  

01/18/2019

 

 

 

 

 

 

 

 

 

 

 

 

 

 


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