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Catalog Number: 10-1935-xx
Description: 5'-Carboxy-Modifier C10
| 10-Carboxy-decyl-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite, N-hydroxysuccinimide ester | ||
| Formula: C23H40N3O6P | M.W.: 485.56 | F.W.: varies, -CO2H = 250.23 |
Diluent: Anhydrous Acetonitrile Add fresh diluent to product vial to recommended concentration and swirl vial occasionally over several minutes until product is completely dissolved. (Some oils may require between 5 and 10 minutes.) Use care to maintain anhydrous conditions. In case of transfer to alternate vial type, ensure recipient vial has been pre-dried. For more information, see http://www.glenres.com/Technical/TB_ABITransfer.pdf. |
| Coupling: No changes needed from standard method recommended by synthesizer manufacturer. |
| Deprotection: See The Glen Report, Volume 15, Number 1, March 2002, page 11 (http://www.glenres.com/GlenReports/GR15-15.html). Technical Bulletin |
| Storage: Freezer storage, -10 to -30°C, dry |
| Stability in Solution: 2-3 days |
| Please Note: 5'-Carboxy-Modifier C10 is offered for sale under license from TriLink BioTechnologies, Inc. It is intended for research and development purposes only, and may not be used for commercial, clinical, diagnostic or any other use. It is covered under US Patent No. 6,320,041. |
| Note: NaOH is not compatible with dmf protecting groups. |
| Catalog Information | Material Safety Data Sheet |
Literature Highlights
DILUTION/COUPLING DATA
The table below shows pack size data and, for solutions, dilutions and approximate couplings based on normal priming procedures. Please link for more detailed usage information with the various synthesizers.
| ABI 392/394 | |||||||||
| Cat.No. | Pack Size | Grams/ Pack | 0.1M Dil. (mL) | LV40 | LV200 | 40nm | 0.2µm | 1µm | 10µm |
| Approximate Number of Additions | |||||||||
| 10-1935-02 | 0.25grams | .25grams | 5.15 | 158.33 | 95 | 59.38 | 43.18 | 31.67 | 7.92 |
| 10-1935-90 | 100µmoles | .049grams | 1 | 20 | 12 | 7.5 | 5.45 | 4 | 1 |
| Expedite | |||||||||
| Cat.No. | Pack Size | Grams/ Pack | Dilution (mL) | Molarity | 50nm | 0.2µm | 1µm | 15µm | |
| Approximate Number of Additions | |||||||||
| 10-1935-02 | 0.25grams | .25grams | 7.68 | .07 | 147.2 | 92 | 66.91 | 9.2 | |
| 10-1935-90 | 100µmoles | .049grams | 1.5 | .07 | 23.6 | 14.75 | 10.73 | 1.48 | |
| Beckman | |||||||||
| Cat.No. | Pack Size | Grams/ Pack | Dilution (mL) | Molarity | 30nm | 200nm | 1000nm | ||
| Approximate Number of Additions | |||||||||
| 10-1935-02 | 0.25grams | .25grams | 7.68 | .07 | 148.8 | 93 | 67.64 | ||
| 10-1935-90 | 100µmoles | .049grams | 1.5 | .07 | 25.2 | 15.75 | 11.45 | ||
01/16/2013 | http://www.glenres.com/ProductFiles/10-1935.html