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Catalog Number: 10-1920-xx
Description: Symmetric Doubler Phosphoramidite
| 1,3-bis-[5-(4,4'-dimethoxytrityloxy)pentylamido]propyl-2-[(2-cyanoethyl)- (N,N-diisopropyl)]-phosphoramidite | ||
| Formula: C64H79N4O10P | M.W.: 1095.32 | F.W.: 351.31 |
Diluent: Anhydrous Acetonitrile |
| Coupling: Synthesis should be carried out on 1000 support. A 15 minute coupling time is recommended for the doubler addition. |
| Deprotection: No changes needed from standard method recommended by synthesizer manufacturer. |
| Storage: Refrigerated storage, maximum of 2-8°C, dry |
| Stability in Solution: 2-3 days |
| Please Note: This product is supplied under license from ISIS Innovation Limited. |
| Catalog Information | Material Safety Data Sheet |
Literature Highlights
| Glen Report 12.1: OLIGONUCLEOTIDE DENDRIMERS: FROM POLY-LABELLED DNA PROBES TO STABLE NANO-STRUCTURES |
DILUTION/COUPLING DATA
The table below shows pack size data and, for solutions, dilutions and approximate couplings based on normal priming procedures. Please link for more detailed usage information with the various synthesizers.
| ABI 392/394 | |||||||||
| Cat.No. | Pack Size | Grams/ Pack | 0.1M Dil. (mL) | LV40 | LV200 | 40nm | 0.2µm | 1µm | 10µm |
| Approximate Number of Additions | |||||||||
| 10-1920-02 | 0.25grams | .25grams | 2.28 | 62.67 | 37.6 | 23.5 | 17.09 | 12.53 | 3.13 |
| 10-1920-90 | 100µmoles | .11grams | 1 | 20 | 12 | 7.5 | 5.45 | 4 | 1 |
| Expedite | |||||||||
| Cat.No. | Pack Size | Grams/ Pack | Dilution (mL) | Molarity | 50nm | 0.2µm | 1µm | 15µm | |
| Approximate Number of Additions | |||||||||
| 10-1920-02 | 0.25grams | .25grams | 3.41 | .07 | 61.8 | 38.63 | 28.09 | 3.86 | |
| 10-1920-90 | 100µmoles | .11grams | 1.5 | .07 | 23.6 | 14.75 | 10.73 | 1.48 | |
| Beckman | |||||||||
| Cat.No. | Pack Size | Grams/ Pack | Dilution (mL) | Molarity | 30nm | 200nm | 1000nm | ||
| Approximate Number of Additions | |||||||||
| 10-1920-02 | 0.25grams | .25grams | 3.41 | .07 | 63.4 | 39.63 | 28.82 | ||
| 10-1920-90 | 100µmoles | .11grams | 1.5 | .07 | 25.2 | 15.75 | 11.45 | ||
08/15/2012 | http://www.glenres.com/ProductFiles/10-1920.html