Glen Report 28.2: Transient Cyanoethylation -An Unexpected Route To Chemical Bleaching Of A Fluorophore

Glen Report 28.2: New Product: Glen-Pak™ DNA 3mg 384-Well Plate

Glen Report 28.2: New Products – AquaPhluor® 593 5’-Phosphoramidite and CPG

Glen Report 28.2: Technical Brief – Fluorescein Labelling – Considering the Options

Glen Report 28.2: New Product - TIPS-5-Ethynyl-dU-CE Phosphoramidite

Glen Report 28.2: Versatile Applications of the Copper(I)-Catalyzed Click Chemistry

Glen Report 28.1: Transient Cyanoethylation - An Unexpected Route To Chemical Bleaching Og A Fluorophore

Glen Report 28.1: New Product - Depurination Resistant dA-CE Phosphoramidite

Glen Report 28.1: Cholesteryl-TEG Phosphoramidites and Supports now Certified BSE/TSE Free

Glen Report 28.1: Technical Brief –1-Ethynyl-dSpacer in the Study of Inter-Strand Crosslinks

Glen Report 28.1: Zip Nucleic Acids (ZNA®) are powerful cationic oligonucleotides for molecular biology, diagnostic and therapeutic applications

Glen Report 27.2: New Product - COT Serinol Phosphoramidite

Glen Report 27.2: Technical Brief - Dual-Labelled Oligos Using Click Chemistry

Glen Report 27.2: New Product - 1- Methyl-PseudoUridine

Glen Report 27.2: New Product - Pac-2'-Amino-dA

Glen Report 27.2: Introducing 2'-OMe-Thiophosphoramidites

Glen Report 27.2: New Product - 1-Ethynyl-dSpacer-CE Phosphoramidite

Glen Report 27.1: Technical Brief - Pseudouridine: A New Perspective On Function And Activity

Glen Report 27.1: Technical Brief - DBCO-dT - An Unusual Case of Iodine Sensitivity

Glen Report 27.1: Technical Brief - Capping and Trityl-Protected Amino-Modifiers

Glen Report 27.1: PC Modifiers

Glen Report 27.1: Photocleavable Biotin Linker for Use in SOMAscanTM

Glen Report 27.1: Technical Brief - APA: An Alternative to AMA Deprotection

Glen Report 27.1: New Products - Dithiol Serinol Phosphoramidite and 3'- Dithiol Serinol CPG

Glen Report 27.1: Reversible Photo-Switching Of DNA Function With Azobenzene-Fethered DNA

Glen Report 26.2: New Click Product - Cyanine 7 Azide

Glen Report 26.2: Technical Brief – Use of Click Chemistry for Possible Crosslinking, Click Synthesis of a Potentially Useful azido support

Glen Report 26.2: Technical Brief - Which 3'-Amino-Modifier?

Glen Report 26.2: New Product - Methylene Blue NHS Ester

Glen Report 26.2: DNA-Mediated Charge Transport: A novel property of DNA with diverse applications

Glen Report 26.2: New Product - 5'-Carboxy-Modifier C5

Glen Report 26.2: New Product - N6-Me-A - Reversible m6A RNA modification

Glen Report 26.2: Reversible m6A RNA modification

Glen Report 26.1: New Product - THPTA - A Water Soluble Click Ligand

Glen Report 26.1: Technical Brief - AMA – Ubiquitous Reagent for Oligo Deprotection

Glen Report 26.1: New Product - 5-Me-dC now compatible with AMA and UltraMild Deprotectio

Glen Report 26.1: Preparation of Bromohexyl-modified oligonucleotides for HaloTag conjugation

Glen Report 26.1: DNA conjugation to Halotagged Protein using Glen Bromohexyl Linker

Glen Report 25.2: Technical Brief - Glen UnySupport now Available with Fast Cleavage

Glen Report 25.2: Technical Brief - Selective Covalent Capture of DNA and RNA Targets With Shielded Covalent Probes Incorporating A Photo-Activated Crosslinker

Glen Report 25.2: Cyanine Dyes - A Personal Perspective

Glen Report 25.2: New Product - 5-Formyl-dC III and the Synthesis of Oligonucleotides Containing All Four Epigenetic Nucleosides

Glen Report 25.2: New Products - TEMPO Spin Labels for Click Chemistry and 5-Ethynyl-dU

Glen Report 25.2: New Product - 5'-Dichloro-Dimethoxy-Fluorescein Phosphoramidite

Glen Report 25.2: New Product - Methylene Blue C3 Phosphoramidite

Glen Report 25.2: Methylene Blue Phosphoramidite for DNA Labelling

Glen Report 25.1: Technical Brief - Amino-Modifiers and Summer Shipping

Glen Report 25.1: Technical Brief - Aldehyde and AminoOxy conjugations

Glen Report 25.1: U.S. Patent No. 8,394,948

Glen Report 25.1: Technical Brief - Side Reaction of Fluorescein during Deprotection with Methylamine

Glen Report 25.1: Antisense Trimer Phosphoramidites - Update

Glen Report 25.1: New Product - (5'S)-5',8-Cyclo-dG - DNA Damage and Repair

Glen Report 24.2: New Products: Universal Hybridcpg™ Solid Supports

Glen Report 24.2: Technical Brief - Improved Conditions For Deprotecting 5-Formyl-Dc

Glen Report 24.2: Technical Brief: Which 5'-Amino-Modifier?

Glen Report 24.2: Technical Brief: Fretmatrix - A Method For Simulation And Analysis Of Fret In Oligos

Glen Report 24.2: Advances In Copper(I)-Catalyzed Azide-Alkyne Cycloaddition (Cuaac) Introducing Oligo-Click

Glen Report 24.2: Technical Brief - Reagents For 5'-Labeling Of Micrornas

Glen Report 24.2: New Product - Alkyne-Modifier Serinol Phosphoramidite

Glen Report 24.2: Antisense Trimer Phosphoramidites - A New Method For Mutagenesis Spanning Entire Genes

Glen Report 24.2: New Product - DBCO-dT For Copper-Free Click Chemistry

Glen Report 24.2: Click Dna And Rna Ligation - A Biocompatible Triazole Linkage

Glen Report 24.1: Technical Brief - Compatibility Of Ultramild Monomers Or Ac-Dc With Hydrazine Reagent

Glen Report 24.1: New Product - 5'-Stearyl Phosphoramidite - An Alternative Lipophilic Carrier

Glen Report 24.1: New Products - Solid, Stable Amino-Modifiers - Pda Amino-Modifiers

Glen Report 24.1: New Products - 6-Hex And 6-Tet Azides

Glen Report 24.1: New Product - Dibenzocyclooctyl (Dbco) Copper-Free Click Chemistry

Glen Report 24.1: New Products: Ab 3900 Columns Containing 1000å Cpg

Glen Report 24.1: New Product - S-Bz-Thiol-Modifier C6-Dt

Glen Report 24.1: Spermine Phosphoramidite: A Potent Modification With Many Applications

Glen Report 23.2: New Products - Bulk Polystyrene Supports

Glen Report 23.2: Technical Brief - Improved Oligo Synthesis Using 2-Amino-Da And Cso Oxidation

Glen Report 23.2: Technical Brief - Deprotection Of Hmdu

Glen Report 23.2: Glen-Pak™ Purification - Then And Now

Glen Report 23.2: New Product - Npom-Caged-Dt

Glen Report 23.2: On-Resin Synthesis Of Maleimido-Oligonucleotides

Glen Report 23.2: New Products - Blackberry® Quencher (Bbq-650®)

Glen Report 23.2: New Product - 5'-Aminooxy-Modifier 11

Glen Report 23.2: Glen Research Epigenetic Bases Report

Glen Report 23.1: Technical Brief - Chemical Phosphorylation – Considering The Options

Glen Report 23.1: Technical Brief - Labelling Carboxy-Modifiers With Multiple Reporter Molecules

Glen Report 23.1: Product Update - Unnatural Base Pairs

Glen Report 23.1: New Product - Ultrafast Photo Cross-Linker

Glen Report 23.1: New Products - Click Chemistry Update

Glen Report 23.1: New Products Prevent Branching At Secondary Amines Using Dci Activator

Glen Report 23.1: Dna Methylation Revisited

Glen Report 22.2: Glen-Pak(Tm) Product Update: New Protocols For Purification

Glen Report 22.1: Glen-Pak™ Product Update: New Protocols For Desalting And Purification

Glen Report 22.2: Technical Brief - Crosslinking With Click Chemistry

Glen Report 22.2: Technical Brief - Symmetrically Branched Four-Arm Dna

Glen Report 22.2: Deprotection - Volume 5 - On-Column Deprotection Of Oligonucleotides In Organic Solvents

Glen Report 22.2: New Products - Azide Tags For Click Chemistry

Glen Report 22.2: New Products - Glen Gel-Pak(Tm) Dna/Rna Desalting And 1000å Glen Unysupport(Tm) Frits

Glen Report 22.2: New Product - Universal Tosyl Phosphoramidite

Glen Report 22.2: New Product: 0.5m Cso For Non-Aqueous Oxidation In Dna Synthesis

Glen Report 22.2: New Products - Dx And Ferrocene-Dt

Glen Report 22.2: 2'-F-Arabinonucleic Acid (2'-F-Ana)

Glen Report 22.1: Technical Brief - Depurination

Glen Report 22.1: Deprotection - Volume 4 - Alternatives To Ammonium Hydoxide

Glen Report 22.1: New Products - 8-Oxo-G Clamp And 5'-Amino-Modifier TEG CE Phosphoramidites

Glen Report 22.1: New Products - A-Tocopherol-TEG Phosphoramidite And 3'-Thiol-Modifier 6 S-S CPG

Glen Report 22.1: New Product - A Dg Amino-Modifier With Improved Hybridization Characteristics

Glen Report 22.1: Saccharin 1-Methylimidazole - An Activator For DNA And RNA Synthesis

Glen Report 22.1: Tc, Tco And Tcnitro: Tricyclic Cytosine Probes Of DNA And RNA Structure

Glen Report 22.1: The Copper(I)-Catalyzed Azide-Alkyne Cycloaddition (Cuaac)

Glen Report 22.1: Simple Oligonucleotide Modification Using Click Chemistry

Glen Report 21.2: Technical Brief - Synthesis Of Long Oligonucleotides

Glen Report 21.2: New Products: Glen-Pak™ DNA Cartridge 3g and DNA 30mg 96-Well Plates

Glen Report 21.1: New Flluorescent Phosphoramidites - Sima (Hex), Dylight™

Glen Report 21.2: New Products - Glen Unysupport™ Frits

Glen Report 21.2: Deprotection - Volume 3 - Dye-Containing Oligonucleotides

Glen Report 21.2: New Product - Azobenzene Phosphoramidite For The Introduction Of Photo-Regulated Functions In Dna

Glen Report 21.2: Non-Aqueous Oxidation For Pace Chemistry

Glen Report 21.2: Tc And TcO: New Tricyclic Fluorescent Cytidine Analogues With A Very Bright Future

Glen Report 21.2: Metallobase Nucleic Acid Modification

Glen Report 21.2: A 3'-Cap For Improved Target Affinity And Specificity

Glen Report 21.2: Purification Of Cleanamp™ Dna Oligonucleotides (Dmt-On)

Glen Report 21.2: 5-Hydroxymethyl-Dc: A New Actor In The Field Of Epigenetics

Glen Report 21.1: Technical Brief – Lna Vs 2'-F-Rna

Glen Report 21.1: New Products - Click Chemistry, Dmf-Dg-5'-Ce Phosphoramidite

Glen Report 21.1: New Products - High Load Glen Unysupport

Glen Report 21.1: Technical Brief - Preparation of oligonucleotides containing abasic sites

Glen Report 21.1: Technical Brief - Preparation Of Oligonucleotiedes Containing Abasic Sites

Glen Report 21.1: New Product - (5‘S)-5',8-Cyclo-Da Ce Phosphoramidite

Glen Report 21.1: Procedure For Synthesis Of Cleanamp™ Primers

Glen Report 21.1: Hot Start Pcr Update: Cleanamp™ Primers

Glen Report 20.1: Improving Universal Support Ii For Oligonucleotide Synthesis

Glen Report 20.2: Site-Specific Incorporation Of Functional Components Into Rna By Transcription Using Unnatural Base Pair Systems

Glen Report 20.2: 5'-Dichloro-Dimethoxy-Fluorescein (Joe Tm) Phosphoramidite

Glen Report 20.2: New Products For Attachment Of Oligonucleotides On Gold Surfaces

Glen Report 20.2: New Universal Support - Glen Unysupport

Glen Report 20.2: Deprotection - Volume 1 - Deprotect To Completion

Glen Report 20.2: Novel Reagents For Modification And Labelling

Glen Report 20.2: Synthesis, Cleavage And Deprotection Of Pace Oligonucleotides

Glen Report 20.2: Phosphonoacetate (Pace) Oligonucleotides

Glen Report 20.1: New Product

Glen Report 20.1: New Products

Glen Report 20.1: New Product - Deuterated 2'-Deoxyguanosine Phosphoramidite

Glen Report 20.1: Technical Brief - New Application For 5'-Ome-Dt Phosphoramidite

Glen Report 20.1: Technical Brief - New Application Of 5-Me-Iso-Dc And Iso-Dg

Glen Report 20.1: More Click Chemistry

Glen Report 20.1: Technical Brief - Purification Of 6-Fam Labelled Oligos Using Glen-Pak™ Cartridges

Glen Report 20.1: Thiophosphoramidites And Their Use In Synthesizing Oligonucleotide Phosphorodithioate Linkages

Glen Report 20.1: An Unnatural Base Pair System For The Expansion Of Genetic Information

Glen Report 19.2: Introducing Thiophosphoramidites

Glen Report 19.2: Technical Brief - About Activators, Now and Tomorrow

Glen Report 19.2: Versatile New Reagents – Pyrene-Du And Perylene-Du

Glen Report 19.2: New Products - 2,6-Diaminopurine-Tom And Fmoc-Amino-Modifier C6 Dt Amidites

Glen Report 19.2: Pyrrolidine Ce Phosphoramidite: A New Base Excision Repair Inhibitor

Glen Report 19.2: Ap-Dc Is Compatible With Pcr And Is Highly Fluorescent

Glen Report 19.2: New Lines Of Monomers - Ht For High Throughput And Lc For Low Cost Rn

Glen Report 19.2: Improved RNA Synthesis Using the Q-Linker For Faster Product Cleavage from Solid-Phase Supports

Glen Report 19.2: Technical Brief - Procedure for Synthesis and Deprotection of Synthetic DNA

Glen Report 19.2: Glen-Pak™ Cartridges – The Ultimate Purification Cartridges

Glen Report 19.1: Large Scale Synthesis Update

Glen Report 19.1: Selenium Derivatization Of Nucleic Acids For X-Ray Crystal Structure Determination

Glen Report 19.1: Quenched Autoligation (Qual) Probes

Glen Report 19.1: 5'-Hexynyl Phosphoramidite - Conjugation With A Click

Glen Report 19.1: Microarrays, Nanotechnology And Beyond

Glen Report 19.1: 1-Methyl-Adenine In Nucleic Acids

Glen Report 19.1: Modified Rna Phosphoramidites Useful In Sirna Research And Biologically Significant 1-Methy-Adenosine

Glen Report 18.1: Fluorous Affinity Purification Of Oligonucleotides

Glen Report 18.1: Synthesis Of Branched Dna With A Comb Structure

Glen Report 18.1: Caps For Increased Duplex Stability And Base-Pairing Fidelity At Termini

Glen Report 18.1: Sulfurizing Reagent II - Stable In Solution And Optimized For RNA Sulfurization

Glen Report 18.1: Trimer Phosphoramidites - Tools For Fine-Tuning Protein Function

Glen Report 18.1 Supplement: Sulfurizing Reagent II And Its Use In Synthesizing Oligonucleotide Phosphorothioates

Glen Report 17.1: Internally Quenched Nucleotide Fluorescent Reporters

Glen Report 17.1: 2'-Fluoro-Rna Monomers

Glen Report 17.1: Expanding Our Repertoire Of Dark Quenchers: Black Hole Quenchers

Glen Report 17.1: Unicap Phosphoramidite, An Alternative To Acetic Anhydride Capping

Glen Report 17.1: Products For Sirna Research

Glen Report 17.1: Introduction

Glen Report 17.2: A Comparative Study Of Commercially Available Universal Supports For Oligonucleotide Synthesis

Glen Report 16.2: New Epoch Products - 5'-Aldehyde-Modifier C2 Phosphoramidite And Gig Harbor Green™ Phosphoramidite

Glen Report 16.2: Still More New Products

Glen Report 16.2: Trimer (Codon) Phosphoramidites Simplify Library Preparation

Glen Report 16.2: Locked Nucleic Acid (Lna™) Phosphoramidites

Glen Report 16.2: Activators, Columns And Plates

Glen Report 16.2: ERAGEN BIOSCIENCES TECHNOLOGY (COURTESY OF ERAGEN BIOSCIENCES)

Glen Report 16.2: Thymine Dimers - Dna Lesions Induced By Sunlight Cis-Syn Thymine Dimer Phosphoramidite Now Available

Glen Report 16.1: Minor Base And Related Novel Phosphoramidites

Glen Report 16.1: Minor Base And Related Novel Phosphoramidites

Glen Report 16.1: Minor Base And Related Novel Phosphoramidites

Glen Report 16.1: Minor Base And Related Novel Phosphoramidites

Glen Report 15.1: A Novel Route To Activated Carboxylate Modified Oligonucleotides

Glen Report 15.1: More And Still More Novel Minor Bases

Glen Report 15.1: Pyrrolo-C - A Novel Fluorescent Nucleoside

Glen Report 15.1: Comparison Of Deprotection Methods For 3'-Pt-Amino-Modifier Cpg

Glen Report 15.1: Redmond Red (Tm) And Yakima Yellow (Tm) Dyes, And Eclipse (Tm) Non-Fluorescent Quencher

Glen Report 14.1: Product Update - How Are Methyl Triester Linkages Prepared?

Glen Report 14.1: New Opec™ Reagents For Synthesis By Native Ligation Of Oligonucleotide-Peptide Conjugates

Glen Report 14.1: Pc Biotin And Related Photocleavable Modifiers

Glen Report 14.1: Preparation Of Oligonucleotides Containing Abasic Sites

Glen Report 14.1: A New Simplified 3'-Amino-Modifier Cpg

Glen Report 14.1: Novel Universal Support Features Rapid Amide-Assisted Dephosphorylation

Glen Report 13.1: Product Update - Which 5'-Amino-Modifier

Glen Report 13.1: Polyplex Synthesizer From Genemachines

Glen Report 13.1: Trityl Groups in the Third Millenium: New Prospectives for Oligonucleotide Chemistry and Beyond

Glen Report 13.1: A Rapid Method for Atomic Mutagenesis of Nucleic Acids

Glen Report 12.1: Product Update - Which Chemical Phosphorylation Reagent?

Glen Report 12.1: More Novel Monomers

Glen Report 12.1: Mermade Instruments

Glen Report 12.1: Poly-Pak Purification Of Labelled Probes

Glen Report 12.1: Tom-Protected Minor Base Rna Phosphoramidites

Glen Report 12.1: Oligonucleotide Dendrimers: From Poly-Labelled Dna Probes To Stable Nano-Structures

Glen Report 11.2: More Novel Monomers

Glen Report 11.2: Alternatives To Expedite Monomers

Glen Report 11.2: Nucleotide Analogs For Interference Mapping Of Rna

Glen Report 11.2: New Columns For Expedite And Lv Applications

Glen Report 11.2: Tom-Protecting-Group™ - A Major Improvement In Rna Synthesis

Glen Report 11.2: Advances in RNA Synthesis and Structural Analysis

Glen Report 11.1: More Novel Monomers

Glen Report 11.1: Update - Universal Supports, Q-Supports

Glen Report 11.1: New Fluorescent Reagents - Tamra-dT Dabcyl-dT

Glen Report 11.1: Using Modified Bases To Optimize Hybridization

Glen Report 11.1: OLIGO AFFINITY SUPPORTS

Glen Report 11.1: The Use Of Puromycin Cpg In Combinatorial Chemistry

Glen Report 10.1: Non-Enzymatic Ligation Of Single-Stranded And Duplex Dna

Glen Report 10.1: More Novel Monomers

Glen Report 10.1: Q-Supports Reduce Cleavage Time To 2 Minutes

Glen Report 10.1: Universal Support Replaces Individual Columns

Glen Report 10.1: New Fluorescent Reagents - Tamra Cpg, Fluorescein-Dt

Glen Report 10.1: Cytofectin Gsv Transfection Protocol

Glen Report 10.1: PREPARING OLIGONUCLEOTIDES FOR ANTISENSE EXPERIMENTS

Glen Report 10.1: Dci - A Logical Alternative Activator

Glen Report 9.1 LV-Polystyrene Columns: Low Volume Polystyrene

Glen Report 9.1: Cyclic Oligonucleotides

Glen Report 9.1 (Oxidation with CSO): Non-Aqueous Oxidation With 10-Camphorsulfonyl-Oxaziridine

Glen Report 9.1: Properties Of Oligonucleotides Containing The Bases P And K

Glen Report 9.1: 3'-Labelling - Dabcyl Cpg, Photolabile 3'-Amino-Cpg

Glen Report 9.1: A Gallery Of Recent Additions

Glen Report 9.1: Protecting Groups For DNA, RNA And 2'-OMe-RRNA Monomers

Glen Report 9.1: A Novel Transfection Reagent

Glen Report 8.2: Rambo Activator - Ethylthiotetrazole

Glen Report 8.2: Transcription Terminator, 2-Thio- And 4-Thio-Thymidine

Glen Report 8.2: Photolabile Support For The Preparation Of 3'-Carboxylates

Glen Report 8.2: 5'-Phosphorylation - Now Compatible With Dmt-On Purification

Glen Report 8.2: 5' Labelling - Fluorescein And Cyanine Dyes, Biotin

Glen Report 8.1: Poly-Pak Ii Cartridges For The 1 µmole Synthesis Scale

Glen Report 8.1: 3'-Terminators

Glen Report 8.1: New Protecting Groups For Dna, Rna And 2'-Ome-Rna Monomers

Glen Report 8.1: 5-Methyl-Isocytidine / Isoguanosine Base Pair

Glen Report 8.1: New Universal And Degenerate Bases

Glen Report 7.1: New Modification Reagents And Supports

Glen Report 7.1: New Minor Bases

Glen Report 7.1: Ultramild Dna Synthesis

Glen Report 7.1: Universal Nucleoside

Glen Report 7.1: Ultrafast Chemistry

Glen Report 7.1: Propynyl-2'-Ome-Rna, Br-U, I-U

Glen Report 6.2: New Minor Bases

Glen Report 6.2: Research Review - Antisense Rna

Glen Report 6.2: Research Review - Antisense Rna

Glen Report 6.2: Ultrafast Dna Synthesis - 10 Minute Deprotection!

Glen Report 6.2: C-5 Propyne Derivatives - Antisense Breakthrough?

Glen Report 6.1: Etheno-Da And Etheno-A* - Fluorescent Monomers

Glen Report 6.1: New Labelling Reagents

Glen Report 6.1: 5' To 3' Synthesis

Glen Report 6.1: Deoxyuridine Derivatives For Internal Modification

Glen Report 6.1: 2'-Ome-Rna Update

Glen Report 6.1: Post-Synthetic Substitution - Convertible Nucleosides