May 2018
GR30.1

Introducing ribo-tCO DBCO-Serinol Phosphoramidite Significant Improvement of CRISPR Specificity with 2’-OMe-PACE Modifications Use of 2’-OMe-PACE Monomers During Oligo Synthesis Methylene Blue II - A Unique Dye Technical Brief – 5’-Phosphorylation of RNA Technical Snippets/Lab Talk/Literature Highlight Portable Data Format (PDF): 819KB

Dec 2017
GR29.1

CDPI₃ MGB™-Oligonucleotide conjugates and their applications 5'-CDPI₃ MGB™ Phosphoramidite and 3'-CDPI₃ MGB™ CPG Studying DNA Repair Pathways Using Site-Specifically Modified Oligonucleotides N-acetylgalactosamine (GalNAc) Oligonucleotide Conjugates Sequence Modification using Glen Research's 5-Modified dU Family Portable Data Format (PDF): 861KB

Dec 2016
GR28.2

Versatile Applications of the Copper(I)-Catalyzed Click Chemistry New Product - TIPS-5-Ethynyl-dU-CE Phosphoramidite Technical Brief – Fluorescein Labelling – Considering the Options New Products – AquaPhluor® 593 5'-Phosphoramidite and CPG NEW PRODUCT: Glen-Pak™ DNA 3mg 384-Well Plate Transient Cyanoethylation - an unexpected route to chemical bleaching of a fluorophore Portable Data Format (PDF): 589KB

May 2016
GR28.1

Zip Nucleic Acids (ZNA®) are powerful cationic oligonucleotides for molecular biology,diagnostic and therapeutic applications Technical Brief –1-Ethynyl-dSpacer in the Study of Inter-Strand Crosslinks Cholesteryl-TEG Phosphoramidites and Support now Certified BSE/TSE Free New Product - Depurination Resistant dA-CE Phosphoramidite Portable Data Format (PDF): 655KB

Dec 2015
GR27.2

New Product - 1-Ethynyl-dSpacer CE Phosphoramidite Introducing 2'-OMe-Thiophosphoramidites New Product - Pac-2-Amino-dA New Product - 1-Methyl-Pseudouridine Technical Brief - Dual-labelled Oligos using Click Chemistry New Product - COT Serinol Phosphoramidite Portable Data Format (PDF): 854KB

May 2015
GR27.1

Reversible photo-switching of DNA function with azobenzene-tethered DNA New Products - Dithiol Serinol Phosphoramidite and 3'- Dithiol Serinol CPG Technical Brief - APA: An alternative to AMA deprotection Photocleavable biotin linker for use in SOMAscan™ PC Modifiers Technical Brief - Capping and Trityl-protected Amino-Modifiers Technical Brief - DBCO-dT - An Unusual Case of Iodine Sensitivity Technical Brief - Pseudouridine: A new perspective on function and activity Portable Data Format (PDF): 760K

Dec 2014
GR26.2

Reversible m⁶A RNA modification New Product - N6-Me-A - Reversible m6A RNA modification New Product - 5'-Carboxy-Modifier C5 DNA-Mediated Charge Transport: A novel property of DNA with diverse applications New Product - Methylene Blue NHS Ester Technical Brief - Which 3'-Amino-Modifier? Technical Brief – Use of Click Chemistry for Possible Crosslinking, Click Synthesis of a Potentially Useful azido support and New Click Product - Cyanine 7 Azide New Product - Disulfo-Cyanine 7 Azide Technical Brief - DBCO-DT - An Unusual Case of iodine Sensitivity Portable Data Format (PDF): 760KB

May 2014
GR26.1

DNA conjugation to Halotagged Protein using Glen Bromohexyl Linker Preparation of Bromohexyl-modified oligonucleotides for HaloTag conjugation New Product - 5-Me-dC now compatible with AMA and UltraMild Deprotection Technical Brief - AMA – Ubiquitous Reagent for Oligo Deprotection New Product - THPTA - A Water Soluble Click Ligand Portable Data Format (PDF): 800KB

Dec 2013
GR25.2

Methylene Blue Phosphoramidite for DNA Labelling New Product - Methylene Blue C3 Phosphoramidite New Product - 5'-Dichloro-Dimethoxy-Fluorescein Phosphoramidite New Products - TEMPO Spin Labels for Click Chemistry and 5-Ethynyl-dU New Product - 5-Formyl-dC III and the synthesis of oligonucleotides containing all four Epigenetic Nucleosides Cyanine Dyes - A personal perspective Technical Brief - Selective covalent capture of DNA and RNA targets with shielded covalent probes incorporating a photo-activated crosslinker Technical Brief - Glen UnySupport now Available with Fast Cleavage Portable Data Format (PDF): 664KBX

May 2013
GR25.1

New Product - (5'S)-5',8-Cyclo-dG - DNA Damage and Repair Antisense Trimer Phosphoramidites - Update Technical Brief - Side Reaction of Fluorescein during Deprotection with Methylamine U.S. Patent No. 8,394,948 Technical Brief - Aldehyde and AminoOxy conjugations Technical Brief - Amino-Modifiers and Summer Shipping Portable Data Format (PDF): 664KB

VOLUME 30 NUMBER 1

CONTENTS

Introducing ribo-tC^O

DBCO-Serinol Phosphoramidite

Significant Improvement of CRISPR Specificity with 2'-OMe-PACE Modifications

Use of 2'-OMe-PACE Monomers During Oligo Synthesis

Methylene Blue II - A Unique Dye

Technical Brief - 5'-Phosphorylation of RNA

Technical Snippets/Lab Talk/Literature Highlight

View Glen Report in Portable Data Format (PDF): 589KB

http://www.glenres.com/GlenReports/GR28-2CONT.html