Duplex StabilizationEpigenetics/DNA Methylation
Serinol COT-Serinol Dabcyl Biotin Fluorescein Rhodamine Cyanine Elitechgroup Dyes and Quencher Black Hole Quencher Blackberry Rhodamine (TAMRA) Acridine DNP Cholesterol Tocopherol Stearyl Psoralen EDTA Ferrocene Methylene Blue Metal Chelates Polyaromic Hydrocarbons Puromycin Quenched Autoligation (QUAL) Probes Photo Regulation
RNA Supports For 3'-Modification TOM-Protected RNA Amidites RNA Supports For TOM RNA Synthesis TBDMS-Protected RNA Amidites HT RNA Amidites UltraMild TBDMS RNA Amidites TBDMS RNA Supports UltraMild Solvents/Reagents Minor RNA Amidites (TOM) RNA Sequence Modifier (TOM-Protected) Minor RNA Amidites (TBDMS-Protected) Minor RNA Triphosphates 2'-OMe-RNA Amidites 2'-OMe-Supports HT 2'-OMe-RNA Amidites Ultramild 2'-OME-RNA Minor 2'-OMe-RNA Amidites 2'-OMe-Thiophosphoramidites 2'-F-RNA Monomers 2'-F-Arabinonucleic Acid (2'-F-ANA)
Dr. Oligo (Catalog as PDF)
Sterling CE PhosphoramiditesDr. Oligo synthesizers belong to a family of synthesizers, including the parallel array synthesizers, Dr. Oligo 96, Dr. Oligo 192, Dr. Oligo 384 and Dr. Oligo 768, manufactured by Biolytic® Lab Performance, Inc. in Fremont, CA. Their web site can be found at: http://www.biolytic.com. Phosphoramidite monomers are packaged in 30mL and 240mL amber bottles for dissolving at a concentration of 1g/20mL and are connected directly to the instrument. Some instruments may also be configured to accept Applied Biosystems serum vials, as shown on page 6.
Every batch of these CE Phosphoramidites is tested as follows
Sterling Solvents/ReagentsAll solvents and reagents are prepared to our exacting specifications to ensure the highest synthesis efficiency and are passed through a 0.2 micron filter during packaging to eliminate particulate contamination. Parallel synthesizers typically use 5-ethylthio-1H-tetrazole (ETT) as activator to minimize the chance of crystallization. ETT is used at a concentration of 0.25M in acetonitrile, which is far below the level at which crystallization may occur.
Ac2O = Acetic Anhydride
Sterling SupportsDr. Oligo instruments are designed for flexibity in the use of supports and columns. They can use fritted plates with loose CPG (page 8) and AB 3900 style polystyrene and CPG columns. Glen UnySupport™ 40 nmole frits can also be used.
Dr. Oligo instruments are designed for flexibity in the use of supports and columns. They can use fritted plates with loose CPG (page 8) and AB 3900 style polystyrene and CPG columns. Glen UnySupport™ 40 nmole frits can also be used.
OLIGONUCLEOTIDE PURIFICATIONBiolytic Labs. also offers the innovative Dr. Oligo Processor for high throughput purification of oligonucleotides using Glen-Pak™ DNA Purification Cartridges: https://www.biolytic.com/p-6814-dr-oligo-processor-fully-automated.aspx.